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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2{A,C}.p2

Z-value: 2.744

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_121103670	8.569	NM_002193	INHBB	inhibin, beta B
chr7_-_44365019	6.815	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr8_-_144512601	6.191	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr19_-_18717467	5.906		CRLF1	cytokine receptor-like factor 1
chr2_+_42275017	5.560	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr8_-_80679897	5.509	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr15_-_55880508	5.482		PYGO1	pygopus homolog 1 (Drosophila)
chr14_-_65346554	5.386		SPTB	spectrin, beta, erythrocytic
chr3_-_38691118	5.321	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr19_-_15311773	5.156	NM_000435	NOTCH3	notch 3
chrX_+_152953751	4.997	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr9_+_95947211	4.972	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr19_-_18717631	4.948	NM_004750	CRLF1	cytokine receptor-like factor 1
chr2_+_18059923	4.939	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr6_+_107811272	4.867	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr19_-_18717577	4.846		CRLF1	cytokine receptor-like factor 1
chr1_-_16344438	4.816		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr2_-_45236521	4.642	NM_016932	SIX2	SIX homeobox 2
chr6_+_17281773	4.590	NM_001143942	RBM24	RNA binding motif protein 24
chr15_-_48937068	4.571		FBN1	fibrillin 1
chr5_+_6448735	4.570	NM_001145161	UBE2QL1	ubiquitin-conjugating enzyme E2Q family-like 1
chr9_-_35689902	4.543	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr9_-_112260529	4.422	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr1_+_236849753	4.409	NM_001103	ACTN2	actinin, alpha 2
chr16_-_54319966	4.391		IRX3	iroquois homeobox 3
chr2_+_241375235	4.351		GPC1	glypican 1
chr1_-_228135587	4.327	NM_003395	WNT9A	wingless-type MMTV integration site family, member 9A
chr10_-_131762017	4.290	NM_001005463	EBF3	early B-cell factor 3
chr9_-_112083005	4.231	NM_018424 NM_019114	EPB41L4B	erythrocyte membrane protein band 4.1 like 4B
chr2_+_220299699	4.007	NM_005876	SPEG	SPEG complex locus
chr10_-_35103894	4.003	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr10_+_11784355	3.965	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr8_+_142402108	3.886
chr11_-_65640199	3.886	NM_016938	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr5_+_6449114	3.854		UBE2QL1	ubiquitin-conjugating enzyme E2Q family-like 1
chr20_-_3662635	3.825	NM_025220 NM_153202	ADAM33	ADAM metallopeptidase domain 33
chr8_-_75233461	3.818	NM_020647	JPH1	junctophilin 1
chr15_+_96873845	3.803	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr19_+_50706868	3.711	NM_001077186 NM_001145809 NM_024729	MYH14	myosin, heavy chain 14, non-muscle
chr12_+_54378929	3.694	NM_017409	HOXC10	homeobox C10
chr20_-_32031425	3.668	NM_003098	SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr18_+_33877630	3.643	NM_025135	FHOD3	formin homology 2 domain containing 3
chr12_-_124018428	3.558		RILPL1	Rab interacting lysosomal protein-like 1
chr9_-_140196702	3.553	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr11_+_12695851	3.461	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_239756672	3.395	NM_057179	TWIST2	twist homolog 2 (Drosophila)
chr1_-_40042415	3.383		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr15_+_65369153	3.368	NM_001101362	KBTBD13	kelch repeat and BTB (POZ) domain containing 13
chr10_+_120789227	3.360	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr3_+_179370779	3.349	NM_003940	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr16_-_54320328	3.349		IRX3	iroquois homeobox 3
chr20_-_590909	3.321	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr2_+_241375030	3.302	NM_002081	GPC1	glypican 1
chr19_+_35521591	3.214	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr6_-_35464716	3.184	NM_003214	TEAD3	TEA domain family member 3
chrX_-_133119475	3.178		GPC3	glypican 3
chr3_+_50192847	3.172	NM_004186	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_124553448	3.164	NM_001242463 NM_058229	FBXO32	F-box protein 32
chr16_+_55358470	3.160	NM_024335	IRX6	iroquois homeobox 6
chr22_-_34316325	3.139	NM_004737 NM_133642	LARGE	like-glycosyltransferase
chr2_+_176994421	3.132	NM_001199747 NM_001199746 NM_019558	HOXD8	homeobox D8
chr1_-_214724844	3.120		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr3_+_159481880	3.113		SCHIP1	schwannomin interacting protein 1
chr16_+_54965110	3.100	NM_001252197 NM_005853	IRX5	iroquois homeobox 5
chr1_+_237205701	3.082	NM_001035	RYR2	ryanodine receptor 2 (cardiac)
chr12_-_33049664	3.082	NM_001005242 NM_004572	PKP2	plakophilin 2
chr14_-_21566497	3.067		ZNF219	zinc finger protein 219
chr1_+_46269283	3.032	NM_015112	MAST2	microtubule associated serine/threonine kinase 2
chr2_+_56411123	3.027	NM_001080433	CCDC85A	coiled-coil domain containing 85A
chr13_-_110959441	3.003	NM_001845	COL4A1	collagen, type IV, alpha 1
chr10_+_123923104	2.990	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr10_+_123922940	2.990		TACC2	transforming, acidic coiled-coil containing protein 2
chr7_-_27239724	2.985	NM_000522	HOXA13	homeobox A13
chr3_-_123167391	2.961	NM_183357	ADCY5	adenylate cyclase 5
chr1_+_95582827	2.926	NM_152487	TMEM56	transmembrane protein 56
chr5_+_7396030	2.913	NM_020546	ADCY2	adenylate cyclase 2 (brain)
chr17_-_74533623	2.901	NM_134268	CYGB	cytoglobin
chrX_+_135229536	2.900	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr15_-_93632161	2.900	NM_020211	RGMA	RGM domain family, member A
chr1_+_201857997	2.873		SHISA4	shisa homolog 4 (Xenopus laevis)
chr2_+_85980600	2.860	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr13_+_110959592	2.828	NM_001846	COL4A2	collagen, type IV, alpha 2
chr20_-_55841090	2.826		BMP7	bone morphogenetic protein 7
chr12_-_29936685	2.825	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr5_-_38556682	2.776	NM_001127671	LIFR	leukemia inhibitory factor receptor alpha
chr5_-_138730884	2.756	NM_001161546	C5orf65	chromosome 5 open reading frame 65
chr19_+_7580987	2.753	NM_018083	ZNF358	zinc finger protein 358
chr6_-_117086812	2.753	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr11_-_1593149	2.728	NM_004420	DUSP8	dual specificity phosphatase 8
chr2_+_36582812	2.725		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr15_+_41221530	2.724	NM_019074	DLL4	delta-like 4 (Drosophila)
chr17_+_46125675	2.718	NM_003204	NFE2L1	nuclear factor (erythroid-derived 2)-like 1
chr2_+_42275936	2.711
chr4_-_174450529	2.707		HAND2	heart and neural crest derivatives expressed 2
chr1_-_184943532	2.666		FAM129A	family with sequence similarity 129, member A
chr2_+_159825083	2.662	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr7_+_140774031	2.647	NM_001195278	LOC100507421	transmembrane protein 178-like
chr7_-_130418859	2.646	NM_138693	KLF14	Kruppel-like factor 14
chr14_+_69726868	2.641		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr17_-_7197866	2.638	NM_015982	YBX2	Y box binding protein 2
chr1_-_40042461	2.635		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr1_+_52608045	2.630	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chrX_+_47078163	2.624		CDK16	cyclin-dependent kinase 16
chr6_+_43738757	2.614		VEGFA	vascular endothelial growth factor A
chr1_-_33168263	2.597		SYNC	syncoilin, intermediate filament protein
chr15_+_84322809	2.592	NM_207517	ADAMTSL3	ADAMTS-like 3
chr17_+_46125725	2.589		NFE2L1	nuclear factor (erythroid-derived 2)-like 1
chr15_-_90294359	2.588	NM_018670	MESP1	mesoderm posterior 1 homolog (mouse)
chr1_-_214724565	2.582		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr2_+_56411756	2.578
chr14_-_61190458	2.574	NM_017420	SIX4	SIX homeobox 4
chr17_-_74707000	2.572	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr22_-_50699938	2.572	NM_002969	MAPK12	mitogen-activated protein kinase 12
chr22_-_50699687	2.571		MAPK12	mitogen-activated protein kinase 12
chr5_-_16617085	2.559	NM_001034850	FAM134B	family with sequence similarity 134, member B
chr19_-_49865638	2.546	NM_003598	TEAD2	TEA domain family member 2
chr7_+_70597788	2.527	NM_022479	WBSCR17	Williams-Beuren syndrome chromosome region 17
chr15_+_51633712	2.526	NM_181789	GLDN	gliomedin
chr15_+_99645152	2.513	NM_015286 NM_145728	SYNM	synemin, intermediate filament protein
chr3_+_32148136	2.513		GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr1_+_44444986	2.505		B4GALT2	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr5_-_168727715	2.499	NM_003062	SLIT3	slit homolog 3 (Drosophila)
chr2_+_205410716	2.496		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chrX_-_71933709	2.489	NM_001122670 NM_001172436 NM_002637	PHKA1	phosphorylase kinase, alpha 1 (muscle)
chr5_-_172662085	2.487	NM_001166175 NM_001166176 NM_004387	NKX2-5	NK2 homeobox 5
chr10_-_100027943	2.484	NM_032211	LOXL4	lysyl oxidase-like 4
chr22_+_33197744	2.481		TIMP3	TIMP metallopeptidase inhibitor 3
chr2_+_46769821	2.473	NM_012249	RHOQ	ras homolog gene family, member Q
chrX_-_34675366	2.471	NM_031442	TMEM47	transmembrane protein 47
chr1_-_40042519	2.467	NM_001135653 NM_001135654 NM_003819	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr16_-_54318889	2.465		IRX3	iroquois homeobox 3
chr20_-_60942300	2.460	NM_005560	LAMA5	laminin, alpha 5
chr2_+_241375207	2.454		GPC1	glypican 1
chr3_+_32148000	2.454	NM_015141	GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr2_-_183902747	2.454		NCKAP1	NCK-associated protein 1
chr19_+_45312294	2.436	NM_001013257 NM_005581	BCAM	basal cell adhesion molecule (Lutheran blood group)
chr1_-_1284297	2.426	NM_004421	DVL1	dishevelled, dsh homolog 1 (Drosophila)
chr8_+_30241943	2.418	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr20_-_62130390	2.413	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr7_+_128470462	2.412	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr2_+_46769892	2.409		RHOQ	ras homolog gene family, member Q
chr4_+_4861371	2.399	NM_002448	MSX1	msh homeobox 1
chr14_-_102976096	2.397	NM_152326	ANKRD9	ankyrin repeat domain 9
chr7_-_82073020	2.374	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_+_15218141	2.366	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_-_47207425	2.356	NM_001184975	PACSIN3	protein kinase C and casein kinase substrate in neurons 3
chr11_-_57092283	2.356	NM_033396	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr1_-_22469414	2.349	NM_030761	WNT4	wingless-type MMTV integration site family, member 4
chr2_+_220306772	2.346		SPEG	SPEG complex locus
chr10_-_30025754	2.339		SVIL	supervillin
chr17_-_46115135	2.337	NM_016429	COPZ2	coatomer protein complex, subunit zeta 2
chr22_-_19511777	2.332		CLDN5	claudin 5
chr4_+_148653452	2.325	NM_024605	ARHGAP10	Rho GTPase activating protein 10
chr5_-_134369841	2.321	NM_002653	PITX1	paired-like homeodomain 1
chr14_-_38725253	2.306		CLEC14A	C-type lectin domain family 14, member A
chr17_+_8924822	2.301	NM_004822	NTN1	netrin 1
chrX_-_133119624	2.299	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr22_+_51113069	2.297	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr4_-_174450343	2.295		HAND2	heart and neural crest derivatives expressed 2
chr5_-_151304322	2.276	NM_000171 NM_001146040	GLRA1	glycine receptor, alpha 1
chr17_-_7197811	2.265		YBX2	Y box binding protein 2
chr13_-_76055872	2.262	NM_014832	TBC1D4	TBC1 domain family, member 4
chr6_-_105584542	2.260	NM_007073	BVES	blood vessel epicardial substance
chr7_-_100493481	2.258	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr17_+_65040651	2.248	NM_000727	CACNG1	calcium channel, voltage-dependent, gamma subunit 1
chr1_+_178063237	2.240		RASAL2	RAS protein activator like 2
chr8_-_38325825	2.232		FGFR1	fibroblast growth factor receptor 1
chr18_+_29078026	2.224	NM_001943	DSG2	desmoglein 2
chr12_-_124018066	2.217	NM_178314	RILPL1	Rab interacting lysosomal protein-like 1
chr10_-_116527955	2.214		ABLIM1	actin binding LIM protein 1
chr6_-_46459010	2.209	NM_001251974	RCAN2	regulator of calcineurin 2
chr17_+_46125724	2.204		NFE2L1	nuclear factor (erythroid-derived 2)-like 1
chr14_+_100259445	2.202	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr6_+_43738177	2.198		VEGFA	vascular endothelial growth factor A
chr17_+_40913233	2.197		RAMP2	receptor (G protein-coupled) activity modifying protein 2
chr14_+_69726680	2.193	NM_001168368 NM_020692	GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr22_+_31489343	2.191		SMTN	smoothelin
chr16_-_54962707	2.179		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr3_+_135684463	2.171	NM_001190447 NM_002718	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_6186878	2.158		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_-_119234859	2.151	NM_171997	USP2	ubiquitin specific peptidase 2
chr20_-_62680880	2.150	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr3_-_48130283	2.146		MAP4	microtubule-associated protein 4
chr2_-_218843541	2.140		TNS1	tensin 1
chr8_-_10587942	2.139	NM_031439	SOX7	SRY (sex determining region Y)-box 7
chr9_-_114245815	2.134		KIAA0368	KIAA0368
chr15_-_64338519	2.132	NM_014326	DAPK2	death-associated protein kinase 2
chr3_+_42700837	2.128		ZBTB47	zinc finger and BTB domain containing 47
chr14_-_91282642	2.124
chr8_+_145321462	2.123	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr16_-_4166185	2.112	NM_001116	ADCY9	adenylate cyclase 9
chr1_-_156647088	2.103	NM_006617	NES	nestin
chr3_+_135684606	2.102		PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_119187811	2.097	NM_006500	MCAM	melanoma cell adhesion molecule
chr9_+_133320247	2.094		ASS1	argininosuccinate synthase 1
chr14_-_25519076	2.093	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr16_-_70719693	2.089		MTSS1L	metastasis suppressor 1-like
chr19_-_46272102	2.087
chrX_+_47078053	2.085	NM_006201	CDK16	cyclin-dependent kinase 16
chr2_+_205410556	2.074		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.04	1.37e-24	GO:0032502	developmental process
2.15	3.03e-23	GO:0048856	anatomical structure development
2.90	4.49e-23	GO:0009653	anatomical structure morphogenesis
2.07	1.28e-22	GO:0007275	multicellular organismal development
2.16	2.85e-20	GO:0048731	system development
2.28	1.84e-16	GO:0048869	cellular developmental process
2.27	1.23e-15	GO:0030154	cell differentiation
1.65	2.64e-15	GO:0032501	multicellular organismal process
1.51	3.00e-15	GO:0050794	regulation of cellular process
1.44	1.94e-14	GO:0065007	biological regulation
1.47	2.56e-14	GO:0050789	regulation of biological process
5.08	7.85e-14	GO:0061061	muscle structure development
2.44	1.82e-13	GO:0007399	nervous system development
2.89	7.51e-13	GO:0048468	cell development
3.36	7.66e-12	GO:0009887	organ morphogenesis
3.27	1.41e-11	GO:0032989	cellular component morphogenesis
2.13	2.92e-11	GO:0048513	organ development
5.50	4.11e-11	GO:0007517	muscle organ development
3.96	1.74e-10	GO:0048598	embryonic morphogenesis
3.02	2.14e-10	GO:0009790	embryo development
1.99	3.46e-10	GO:0048523	negative regulation of cellular process
3.19	3.57e-10	GO:0000902	cell morphogenesis
1.93	4.89e-10	GO:0048519	negative regulation of biological process
3.35	1.89e-09	GO:0000904	cell morphogenesis involved in differentiation
2.61	1.36e-08	GO:0048699	generation of neurons
2.60	1.60e-08	GO:0009888	tissue development
2.55	1.79e-08	GO:0022008	neurogenesis
3.29	2.08e-08	GO:0072358	cardiovascular system development
3.29	2.08e-08	GO:0072359	circulatory system development
1.66	7.72e-08	GO:0060255	regulation of macromolecule metabolic process
2.74	1.10e-07	GO:0030182	neuron differentiation
1.61	3.81e-07	GO:0031323	regulation of cellular metabolic process
3.03	4.48e-07	GO:0048858	cell projection morphogenesis
1.77	5.10e-07	GO:0048522	positive regulation of cellular process
1.56	5.22e-07	GO:0019222	regulation of metabolic process
3.01	5.84e-07	GO:0032990	cell part morphogenesis
2.86	6.36e-07	GO:0048666	neuron development
3.78	7.32e-07	GO:0001944	vasculature development
1.60	9.84e-07	GO:0080090	regulation of primary metabolic process
6.44	1.45e-06	GO:0030326	embryonic limb morphogenesis
6.44	1.45e-06	GO:0035113	embryonic appendage morphogenesis
3.54	1.79e-06	GO:0001501	skeletal system development
5.78	2.91e-06	GO:0048736	appendage development
5.78	2.91e-06	GO:0060173	limb development
3.04	5.26e-06	GO:0048667	cell morphogenesis involved in neuron differentiation
3.07	7.21e-06	GO:0007409	axonogenesis
2.99	8.35e-06	GO:0048812	neuron projection morphogenesis
5.68	1.10e-05	GO:0035107	appendage morphogenesis
5.68	1.10e-05	GO:0035108	limb morphogenesis
3.66	1.11e-05	GO:0001568	blood vessel development
2.22	1.52e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.65	1.54e-05	GO:0048518	positive regulation of biological process
2.58	1.58e-05	GO:0030030	cell projection organization
1.65	2.73e-05	GO:0031326	regulation of cellular biosynthetic process
1.66	3.24e-05	GO:0010468	regulation of gene expression
1.51	5.10e-05	GO:0023052	signaling
1.63	5.14e-05	GO:0009889	regulation of biosynthetic process
2.22	5.57e-05	GO:0050793	regulation of developmental process
4.82	5.72e-05	GO:0042692	muscle cell differentiation
2.16	6.11e-05	GO:0009605	response to external stimulus
3.80	7.19e-05	GO:0048514	blood vessel morphogenesis
1.66	8.11e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.65	8.84e-05	GO:0010556	regulation of macromolecule biosynthetic process
2.71	1.06e-04	GO:0031175	neuron projection development
1.83	1.73e-04	GO:0023051	regulation of signaling
1.52	1.74e-04	GO:0007165	signal transduction
5.32	2.08e-04	GO:0003007	heart morphogenesis
3.08	2.47e-04	GO:0007411	axon guidance
2.29	2.56e-04	GO:2000026	regulation of multicellular organismal development
2.10	3.19e-04	GO:0042127	regulation of cell proliferation
2.17	3.52e-04	GO:0040011	locomotion
3.48	3.71e-04	GO:0007507	heart development
1.86	5.23e-04	GO:0009966	regulation of signal transduction
3.30	5.28e-04	GO:0045596	negative regulation of cell differentiation
2.41	6.25e-04	GO:0010629	negative regulation of gene expression
4.57	6.89e-04	GO:0014706	striated muscle tissue development
1.90	7.28e-04	GO:0051239	regulation of multicellular organismal process
1.63	9.84e-04	GO:0051252	regulation of RNA metabolic process
1.64	1.12e-03	GO:0006355	regulation of transcription, DNA-dependent
3.34	1.35e-03	GO:0003002	regionalization
2.88	1.51e-03	GO:0007389	pattern specification process
4.28	1.70e-03	GO:0030111	regulation of Wnt receptor signaling pathway
2.26	1.81e-03	GO:0045595	regulation of cell differentiation
4.04	1.82e-03	GO:0045165	cell fate commitment
5.22	1.83e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
2.92	1.84e-03	GO:0051093	negative regulation of developmental process
2.05	1.88e-03	GO:0010605	negative regulation of macromolecule metabolic process
2.78	1.97e-03	GO:0043009	chordate embryonic development
1.55	1.98e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.56	1.99e-03	GO:0048646	anatomical structure formation involved in morphogenesis
4.18	2.34e-03	GO:0060537	muscle tissue development
2.46	2.44e-03	GO:0006935	chemotaxis
2.46	2.44e-03	GO:0042330	taxis
2.75	2.49e-03	GO:0009792	embryo development ending in birth or egg hatching
11.24	2.68e-03	GO:0045446	endothelial cell differentiation
1.41	2.71e-03	GO:0051716	cellular response to stimulus
1.53	2.75e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.69	2.76e-03	GO:0007166	cell surface receptor linked signaling pathway
1.94	3.09e-03	GO:0010941	regulation of cell death
2.16	3.15e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.95	3.23e-03	GO:0042981	regulation of apoptosis
1.16	3.39e-03	GO:0009987	cellular process
1.98	3.50e-03	GO:0009892	negative regulation of metabolic process
2.28	3.52e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.59	3.76e-03	GO:0042221	response to chemical stimulus
2.27	3.83e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.24	3.94e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.94	4.17e-03	GO:0043067	regulation of programmed cell death
2.23	4.46e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.86	4.90e-03	GO:0031325	positive regulation of cellular metabolic process
1.29	5.19e-03	GO:0050896	response to stimulus
2.05	5.31e-03	GO:0031328	positive regulation of cellular biosynthetic process
10.26	5.37e-03	GO:0003158	endothelium development
2.95	6.61e-03	GO:0007423	sensory organ development
4.05	7.56e-03	GO:0048705	skeletal system morphogenesis
2.02	8.34e-03	GO:0009891	positive regulation of biosynthetic process
2.47	8.82e-03	GO:0051094	positive regulation of developmental process
2.62	8.93e-03	GO:0060429	epithelium development
2.43	9.15e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.16	9.48e-03	GO:0010628	positive regulation of gene expression
3.15	1.05e-02	GO:0002009	morphogenesis of an epithelium
2.06	1.07e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
2.07	1.16e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.14	1.19e-02	GO:0031327	negative regulation of cellular biosynthetic process
5.81	1.19e-02	GO:0048704	embryonic skeletal system morphogenesis
1.79	1.41e-02	GO:0009893	positive regulation of metabolic process
2.30	1.47e-02	GO:0045892	negative regulation of transcription, DNA-dependent
2.20	1.53e-02	GO:0009725	response to hormone stimulus
1.95	1.56e-02	GO:0031324	negative regulation of cellular metabolic process
2.79	1.66e-02	GO:0048729	tissue morphogenesis
2.13	1.81e-02	GO:0051254	positive regulation of RNA metabolic process
2.10	1.93e-02	GO:0009890	negative regulation of biosynthetic process
2.11	2.10e-02	GO:0009719	response to endogenous stimulus
2.25	2.24e-02	GO:0051253	negative regulation of RNA metabolic process
3.50	2.37e-02	GO:0009952	anterior/posterior pattern formation
3.44	3.03e-02	GO:0001525	angiogenesis
4.76	3.09e-02	GO:0032355	response to estradiol stimulus
3.42	3.28e-02	GO:0006936	muscle contraction
4.70	3.49e-02	GO:0048706	embryonic skeletal system development
6.58	3.90e-02	GO:0035050	embryonic heart tube development
5.11	3.91e-02	GO:0060538	skeletal muscle organ development
2.37	3.91e-02	GO:0032583	regulation of gene-specific transcription
2.51	4.25e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
7.61	4.69e-02	GO:0035051	cardiac cell differentiation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.62	1.39e-06	GO:0030054	cell junction
6.74	3.43e-06	GO:0005604	basement membrane
3.09	3.25e-05	GO:0005578	proteinaceous extracellular matrix
4.77	5.29e-05	GO:0044420	extracellular matrix part
2.80	9.48e-05	GO:0031012	extracellular matrix
3.47	2.02e-03	GO:0070161	anchoring junction
3.88	7.25e-03	GO:0044449	contractile fiber part
3.78	9.59e-03	GO:0030016	myofibril
3.56	1.77e-02	GO:0043292	contractile fiber
1.47	2.46e-02	GO:0044459	plasma membrane part
6.21	2.65e-02	GO:0030018	Z disc
3.17	3.41e-02	GO:0005912	adherens junction
3.79	3.68e-02	GO:0030017	sarcomere
1.30	4.85e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.40	1.06e-08	GO:0001071	nucleic acid binding transcription factor activity
2.40	1.06e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
2.23	5.53e-07	GO:0030528	transcription regulator activity
1.31	1.75e-06	GO:0005515	protein binding
2.55	2.89e-05	GO:0008092	cytoskeletal protein binding
2.36	2.91e-05	GO:0043565	sequence-specific DNA binding
1.15	1.46e-04	GO:0005488	binding
2.69	2.69e-03	GO:0003779	actin binding
4.89	2.84e-02	GO:0019902	phosphatase binding